Owning identified the palmitoylation motif of APLNR, we designed a short substrate sequence to competitively inhibit the palmitoylation of endogenous APLNR. This competitive peptide, which targets the APLNR palmitoylation web site together with morphine, can inhibit the event of NCP, including pain incidence, microglial activation, and inflammatory component release https://jamesc184ctl1.wikilentillas.com/user