Thinking about the Energetic intermediates, the crown ether ring of icotinib is oxidated to open up to kind an aldehyde; the indolylidene ring of famitinib is oxidated accompanied by rearrangement to form a quinone- imine; the α, β-unsaturated carbonyl group of allitinib is oxidated to form an epoxide, these intermediates https://lioydsmeds.com/product/buy-tagrisso-online/