Most eukaryotic chromosomes bend back on them selves to kind a physical loop with the telomere. The existence of these loops, aptly named t-loops, was very first established by electron microscopy of purified human telomeres that were stripped in their proteins and stabilized by crosslinking (Griffith et al. Not long https://titusitqdp.ltfblog.com/27803754/the-fact-about-fox-eyes-ğörsel-that-no-one-is-suggesting