There's a launch of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors in the dorsal horn to lower afferent suffering transmission and make analgesia. As a result, medications like clonidine that focus on alpha-2 receptors can impact the transmission of discomfort. Clonidine treats high blood pressure https://vonb482lsv6.mysticwiki.com/user